Abstract
Background: Systemic inflammation is highly prevalent in critically ill patients and contributes to morbidity and mortality. Reliable biomarkers are essential for timely diagnosis and prognosis.
Objective: To determine the correlation among WBC count, NLR, and CRP in ICU patients and evaluate their diagnostic utility.
Methods: A cross-sectional study was conducted on 73 ICU patients. CBC and differential counts were used to compute NLR; CRP was measured via chemiluminescent immunoassay. Correlation testing and ROC analysis were performed.
Results: Leukocytosis was found in 57.5% of patients, elevated NLR (>3.53) in 79.5%, and severe CRP elevation in 53.4%. A significant correlation was observed between NLR and CRP (r=0.440, p<0.001). ROC analysis showed NLR was more sensitive (AUC=0.644) than CRP (AUC=0.611).
Conclusion: NLR demonstrated better diagnostic sensitivity than CRP and can serve as a rapid, cost-effective marker for inflammation in ICU patients
Objective: To determine the correlation among WBC count, NLR, and CRP in ICU patients and evaluate their diagnostic utility.
Methods: A cross-sectional study was conducted on 73 ICU patients. CBC and differential counts were used to compute NLR; CRP was measured via chemiluminescent immunoassay. Correlation testing and ROC analysis were performed.
Results: Leukocytosis was found in 57.5% of patients, elevated NLR (>3.53) in 79.5%, and severe CRP elevation in 53.4%. A significant correlation was observed between NLR and CRP (r=0.440, p<0.001). ROC analysis showed NLR was more sensitive (AUC=0.644) than CRP (AUC=0.611).
Conclusion: NLR demonstrated better diagnostic sensitivity than CRP and can serve as a rapid, cost-effective marker for inflammation in ICU patients